Before taking this medicine. If symptoms do not improve after 7 days, the clinical situation should be reviewed. While fatigue in MS is related to the disease itself, other MS-related factors may contribute to or. Background Idiopathic normal-pressure hydrocephalus (iNPH) is a distinct form of dementia, characterized by gait ataxia, cognitive impairment and urinary incontinence. Sunosi is similar to Provigil in that they are both used to increase wakefulness in people with excessive sleepiness related to. 2 mmoL). Nuvigil is known to last longer in. Achieving decompression without CSF over-drainage remains a challenge in hydrocephalus. dryness of the skin. Beatrix Boros/Stocksy. This means that the opening pressure varies depending on the body position of the patient. We found the Certas TM valve valuable in the treatment of hydrocephalus, usability of the TMS was high because it is small and portable, but in some cases we experienced adjustment problems with the first procedures performed by a surgeon, indicating that there is a learning curve. ADD TO CART. The medication is also used by the military, by go-getters in tech and big business and by surgeons performing long and complicated procedures. indigestion. Modafinil (drug brand name: Provigil) has various mechanisms of action. Over the past several years, there has been a paradigm. Never share your medicine with anyone. Although. Modafinil's mechanism of action is still somewhat elusive, but it is known to stimulate the brain's histamine (HA), norepinephrine (NE), serotonin (5-HT), dopamine (DA), and orexin systems. Learn more about its features, benefits and clinical outcomes in this brochure from Aesculap, a leading provider of surgical and medical solutions. Modafinil (2-[(Diphenylmethyl) sulfinyl] acetamide, Provigil) is an FDA-approved medication with wake-promoting properties. Modafinil is a prescription drug that promotes wakefulness. Modafinil tablets are used to treat excessive sleepiness, but not the obstruction or medical condition that is causing OSA. comModafinil for anxiety is a kind of medication that is only attained through prescription. Common nootropics include modafinil, methylphenidate (Ritalin), and piracetam. Modafinil administration has resulted in cognitive improvement in patients with attention-deficit hyperactivity disorder, major depression, and schizophrenia and in healthy populations (), as well as decreased fatigue in patients with other medical. General information about PROVIGIL Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Giacino at the Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, 125 Nashua St. Amphetamines (e. This medicine does not require any special storage conditions. 75, which is 97% off the average retail price of $719. A patient with theModafinil may also induce its own metabolism. It belongs to a class of drugs known as wakefulness-promoting agents, which can help individuals stay awake and alert. It is used by adults for daytime sleep cause of Narcolepsy and For children enhance focus disorder. Fatigue is an unrelenting, disabling depletion of physical and mental energy, and it affects 80% of people living with multiple sclerosis. 0 valves and Miethke fixed-pressure valves between 2014 and 2019 at our tertiary centre were analysed. Modafinil has also become increasingly used as a recreational drug. 1 List of Excipients. গ্রা. Modvigil is a very effective generic Modafinil medication that is used by students, CEOs, and professionals to stay ahead of the competition. Patients’ underlying conditions were most commonly hydrocephalus (47%) or idiopathic intracranial hypertension (43%). 0 is a shunt system that regulates the cerebrospinal fluid pressure in patients with hydrocephalus. Modafin (modafinil) is a wakefulness-promoting agent for oral administration. Cochlea Medicine & Life Sciences 29%. গ্রা. The recommended dosage of modafinil is 200 or 400 mg/day, given once or twice daily (morning and midday) to patients with narcolepsy. MODAFINIL treats sleep disorders, such as narcolepsy, obstructive sleep apnea, and shift work disorder. Modafinil (Brand Name: Provigil) is a wakefulness-promoting prescription drug that reduces the extreme sleepiness that accompanies sleep disorders including narcolepsy, obstructive sleep apnea, and shift work disorder (SWD). 00 GET 25 % off. গ্রা. trembling or shaking. Modafinil (2- [ (diphenylmethyl) sulfinyl] acetamide) is a manufactured drug that is a Prescription Only Medicine in the UK. Examples include heart-related side effects, such. DEPARTMENT OF HEALTH & HUMAN SERVICES Public Health Service Food and Drug Administration 10903 New Hampshire Avenue Document Control Center - WO66-G609 Silver Spring, MD 20993-0002 Provigil is a prescription medication that is typically covered by commercial insurance. Modafinil was developed in the 1970s by a French professor of experimental medicine to treat narcolepsy and other sleep disorders. Provigil Alternatives Compared. In case of overdose, get medical help or. Buy Modafinil Without a Prescription. Provigil belongs to a class of drugs called. The proGAV 2. The valve combines an innovative adjustable gavitational unit (0-40 cmH2O) with a fixed. Molecular and biologic characteristics of modafinil. )/১০ মি. m. Excipients with known effect. Medication to increase walking speed. An implantable device intended to function as part of a lumboperitoneal, ventriculoperitoneal or ventriculoatrial shunt to regulate the pressure and flow level of cerebrospinal fluid (CSF) from the lumbar spine or brain to the peritoneum/heart right atrium in the management of increased intracranial pressure (e. Exclusion criteria included patients already medicated with modafinil before the first consultation, with history of allergy to the drug or that had no financial condition to buy the medication. SUNOSI (solriamfetol) is a prescription medicine used to improve wakefulness in adults with excessive daytime sleepiness due to narcolepsy or obstructive sleep apnea (OSA). Two clinical trials compared different doses (200 mg and 400 mg) of modafinil with placebo. Modafinil was first prescribed at the Outpatient Facility of Excessive Sleepiness for the narcolepsy patients in 20/03/2008. Modafinil has been linked to irregular heartbeats (arrhythmias) and increases in blood pressure, so you'll need to be regularly monitored during treatment to check for these problems. The present study investigates this development by analyzing shunt- and valve-related outcomes for this. 0. Under the brand name Provigil, modafinil is a central nervous system stimulant that treats sleep disorders by improving wakefulness. Provigil Prices, Coupons and Patient Assistance Programs. com. Off-label it has been used to help people with Parkinson's Disease, ADHD, chronic fatigue. Modafinil is a medication that has been found to be effective in fighting fatigue and improving alertness in people. For this medicine, the following should be. Further, the recently reported cognitive-enhancing actions of (±)-modafinil, especially in methamphetamine abusers ( 12 ) suggest that additional. 75, which is 97% off the average retail price of $719. 0 programmable valve. The exact mechanism of action is unclear. Take a lukewarm shower or bath 60-90 minutes before bed. There are 23,182 people reported to have side effects when taking Provigil. Sunosi. The proGAV 2. +২১৩ মি. This medication contains modafinil. Learn about side effects, drug interactions, dosages, warnings, and more. blue® valve in patients with iNPH. In cases of multiple sclerosis (MS), Provigil may be prescribed off-label to treat fatigue and sleepiness. It may cause serious side effects (e. S. 2 average score. Nuvigil is made of only the R-isomer. Provigil and Nuvigil are prescription drugs used for excessive sleepiness due to certain conditions. গ্রা. Provigil has helped quite a bit but does have some cons. You can go with a methylphenidate to dexmethylphenidate substitution (or vice versa). It is an effective medication approved for promoting wakefulness in individuals with sleep disorders. 2165/00023210-199809040-00006. In human plasma, in vitro, modafinil is moderately bound to plasma protein (~60%, mainly to albumin). This means that it can be optimally adapted to the. Compared with other drugs of this class, Provigil has less of an effect on memory and alertness. No difference was found between modafinil and placebo. 800. Provigil Descriptions Modafinil is used to help people who have narcolepsy, obstructive sleep apnea/hypopnea syndrome (OSAHS), or shift work sleep disorder. , Alzheimer-type and others), ventriculoperitoneal (VP) shunt surgery may offer a curative treatment option to patients. 0 has been developed to address nearly all critical points, which can be recognized during the investigations. A mechanical 'brake' is intended to prevent changes to the valve's performance level in a strong magnetic field. 1. Some people use this “smart drug” to improve their alertness, mental. Provigil Contraindications. People who take modafinil for an extended amount of time may develop drug dependence. gb | instructions for use instructions for use , the progav progav progav ): Depression: Modafinil is an anti-sleeping medication, and it keeps one awake for long periods; lack of sleep and disruption of the normal sleep-wake cycle can lead to the triggering of the onset of mental health issues. Provigil is a brand name version of modafinil. The team compared these medicines with a placebo. 2 Qualitative and Quantitative Composition. Major: Highly clinically. It's considered a controlled substance since this medication has a potential to cause misuse. Possible side effects of modafinil are headaches, dry mouth, nausea, diarrhea, loss of appetite and weight loss. 3 Pharmaceutical. Modafinil is an oral drug that is used to improve wakefulness in patients with excessive sleepiness. Taking a medication with certain vaccines, foods, and other things can affect how the medication works. In 2000, the manufacturer, Cephalon, conducted a study of modafinil in people with MS to evaluate it as a potential treatment for MS-related fatigue. Adzenys ER, Adzenys XR-ODT, and Dyanavel XR The integration of gravitational valves in VPS was established to counteract the hydrostatic draining force and to approach a physiological condition of the cerebrospinal diverting system. But as always, talk to your doctor first before making any. Numerous clinical studies have shown that gravitational valves are able to reduce secondary complications of VPS treatment. Modafinil is well distributed in body tissue with an apparent volume of distribution (~0. Some side effects of modafinil may occur that usually do not need medical attention. Modafinil /armodafinil. PROVIGIL 100 MG. This means that it helps a person feel awake and focused. ; Children 6 to 12 years: 5-10 mL after meals and at bedtime, up to four times a day. Avoid or Use Alternate Drug. This study seeks to describe the utility of the proGAV®2. Modafinil, which has been prescribed in the U. “Evidence that nicotine can produce beneficial effects on some cognitive functions has become firmer and there can now be little doubt that some such effects do occur…”. (An active ingredient is what makes a drug work. From the beginning, we have worked with patients, doctors, distribution partners and critics to confidently deliver a superior product. (A drug class describes a group of. Starting with a low opening pressure setting on a proGAV adjustable shunt valve does not increase the chances of overdrainage complications and reduces the need for repeated readjustments. It has also been used to treat sleep apnea, narcolepsy, and other sleep disorders. I would recommend this medication to anyone who is struggling. Modafinil is a non-amphetamine central nervous system (CNS) stimulant with wakefulness-promoting properties. The American Academy of Sleep Medicine recommends modafinil for people with OSA who still have excessive sleepiness when using CPAP therapy. Modafinil does not cure these conditions and will only work as long as you continue to take it. In many cases, it is. MODAVIGIL® (modafinil) is a wakefulness-promoting agent for oral administration. Experts aren't exactly sure how it works, although they have elucidated that it enhances several chemicals and. Stimulant medication, such as modafinil (Provigil, Alertec), might be prescribed to help you stay awake during the day. This is a decision you and your doctor will make. গ্রা. In OSA, modafinil is recommended for use as an adjunct to standard therapies that treat the underlying airway obstruction. This medicine is available only with your doctor's prescription. Get Coupon. They concluded that the drug. 0 programmable valve in a paediatric population. Sleepiness may be managed with adequate sleep hygiene and scheduled daytime naps. Modafin tablet contains 100 mg of modafinil. o. Progavi Suspension (500 mg+213 mg+325 mg)/10 ml (প্রোগ্যাভি (৫০০ মি. Starting with a low opening pressure setting on a proGAV adjustable shunt valve does not increase the chances of overdrainage complications and reduces the need for repeated readjustments. Sunosi (solriamfetol) is a prescription medicine used for the treatment of excessive sleepiness in adults with narcolepsy or obstructive sleep apnea. Provigil can cause side effects that range from mild to serious. AccessGUDID - proGAV 2. DOSAGE AND ADMINISTRATION In the methylphenidate short-acting category, it's pretty simple. I have been taking 300mg of Provigil for the past 7 yrs. Comparison (placebo vs 400 mg modafinil) in health-related quality of life changes from baseline to 40-week endpoint. Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. and 8 a. An implantable device intended to function as part of a lumboperitoneal, ventriculoperitoneal or ventriculoatrial shunt to regulate the pressure and flow level of cerebrospinal fluid (CSF) from the lumbar spine or brain to the peritoneum/heart right. Optimum Nutrition (ON) 100% Whey Gold Standard Powder - Double Rich Chocolate 2 lb ₹ 3,158. For information regarding participating pharmacies located within a medical facility, please contact customer care at 1-800-407-8156. Modafinil (Provigil) is a novel wakefulness-promoting agent that has been shown to have greater efficacy than placebo in the treatment of attention-deficit hyperactivity disorder (ADHD) in children and adults. Increased monitoring of BP may be appropriate during therapy. It works by altering neurotransmitters in the brain. Besides being structurally unique, the neurophysiological properties of modafinil are. Although the VPS extends survival. Provigil is a type of stimulant medication. In order to configure the proGAV according to the patient´s individual needs, the surgeon determines. +৩২৫ মি. Mechanism of Action. As such, it has a “low potential for abuse and low risk of dependence” . 50 ₹ 3,946. The number of patients receiving modafinil increased almost 10-fold during the study period, from 57 768 in 2002 to 555 691 in 2009. Either the side effects were intolerable, or the medicine just didn't work. 0 programmable valve in a paediatric population. লি. Overall rating 5. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. K J McClellan. GB 3 INSTRUCTIONS FOR USE CONTENT The INDICATION 3 DESCRIPTION OF THE INSTRUMENTS 3 proGAV 2. You should avoid alcohol while taking modafinil (Provigil), as well. Some people need treatment with methylphenidate (Ritalin, Concerta, others) or amphetamines (Adderall XR 10,. It’s most often used to treat excessive sleepiness caused by narcolepsy, obstructive sleep apnea, and shift work. Modafinil is the world’s first safe “smart drug”, researchers at Harvard and Oxford universities have said, after performing a comprehensive review of the drug. 1. Modafinil is a central nervous system (CNS) stimulant medication used primarily to help people remain awake, combat fatigue, and increase concentration. This guideline, in conjunction with the accompanying. 0 provides effective decompression of hydrocephalic patients, significantly reduces the number of valve revisions per patient and had a significantly greater mean time to revision than fixed-pressure valves. Buy Progermina Suspension Online. It is an effective medication, safe and does not have any severe side effects. Although it was specifically designed for treating excessive daytime sleepiness, it is more popularly used off-label to promote focus, boost memory, and ultimately increase productivity. Department of Neurosurgery, School of Medicine, Second Affiliated Hospital, Zhejiang University, Hangzhou, China; Objective: To evaluate the outcomes and prognostic factors of ventriculoperitoneal shunts (VP-shunts) in patients with idiopathic normal-pressure hydrocephalus (iNPH) at 6 months and 2 years after surgery. Provigil may also be used for purposes not listed in this medication guide. Similar to Provigil, Nuvigil ( amodafonil) is a prescription stimulant that can help keep you awake and reduce EDS associated with narcolepsy. Before taking this medicine. Dosage in Narcolepsy and Obstructive Sleep Apnea (OSA) The recommended dosage of PROVIGIL for patients with narcolepsy or OSA is 200 mg taken orally once a day as a single dose in the morning. You should not use this medicine if you are allergic to armodafinil or modafinil (Provigil). Progavi is indicated in Gastric reflux, Heartburn, Flatulence associated with gastric reflux, Heartburn of pregnancy, All cases of epigastric and retrosternal distress where the. What is PROVIGIL? PROVIGIL is a prescription medicine used to improve wakefulness in adults who are very sleepy due to one of the following diagnosed sleep disorders: narcolepsy; obstructive sleep apnea (OSA). Armodafinil promotes wakefulness. Other countries around the world categorize Modafinil similarly. Using a placebo helps researchers learn if results are due to a medicine or chance. My father was depressed most of his adult years, so mine is partly genetic. This is a decision you and your doctor will make. It's similar to the medication modafinil (Provigil). For the full list of excipients, see Section 6. difficulty having a bowel movement. Use this coupon to get this price at any SAMS PHARMACY location. Search for termsModafinil is a prescription-only drug in most Western countries. It can help increase your wakefulness if you have EDS due to obstructive sleep apnea (OSA) or narcolepsy. com newsletters for the latest medication news, new drug approvals, alerts and updates. Modafinil, sold under the brand name Provigil among others, is a central nervous system (CNS) stimulant medication used to treat sleepiness due to narcolepsy, shift work sleep disorder, and obstructive sleep apnea. Then they stopped each medication and waited two weeks before starting the next. However, as discussed above, sodium oxybate (e. Modafinil is well distributed in body tissue with an apparent volume of distribution (~0. You should. 7 % off 5. Modafinil (Provigil) has a unique structure and is not a stimulant like Adderall, but it does have stimulant-like effects and improves alertness, enhances thinking and perception, in addition to helping to keep people awake. As mentioned above, modafinil is a wakefulness-promoting medication used to treat excessive daytime sleepiness. Modafinil, sold under the name Provigil, is a stimulant that some have dubbed the "genius pill. Dyspepsia, associated w/, gastric reflux, reflux oesophagitis, heartburn,. You should not use this medicine if you have had an allergic reaction to modafinil or other similar medicines (such as armodafinil, Nuvigil®). It works by promoting wakefulness. 2273 100 Years of Cleveland Clinic This medicine is available only with your doctor's prescription. 2, 3 Several tests such as the Epworth sleepiness scale 1 were used to assess the outcomes. Provigil (modafinil) is a prescription drug used to treat excessive sleepiness. Notably, modafinil has fewer side effects and is better tolerated than traditional stimulant drugs such as Adderall and Vyvanse. Posted by Dr. and Physical Medicine Devices Office of Device Evaluation Center for Devices and Radiological Health Enclosure Carlos L. Results. Study drugs. গ্রা. Provigil (modafinil) is a stimulant used to promote wakefulness in patients with narcolepsy, obstructive sleep apnea, and shift work sleep disorder. Study record managers: refer to the Data Element Definitions if submitting registration or results information. Modafinil is a prescription medication known as a synthetic stimulant, smart drug, or smart protein, and can only be obtained with a doctor’s prescription. Provigil is a brand-name drug used to treat daytime sleepiness. Modafinil is a prescription medication, and its off-label use for cognitive enhancement in healthy individuals raises ethical and legal concerns. The primary medical approach to narcolepsy involves prescribed medication. Provigil (modafinil) is a brand-name prescription medication. 0® (04041906140199)- PROGAV 2. Buy medicine online and get the fastest delivery and exciting offers. Modafinil is a prescription medication classified as a eugeroic, a type of wakefulness-promoting agent. However, a retrospective analysis of the use of antihypertensive medication in these studies showed that a greater proportion of patients on PROVIGIL (modafinil) required new or increased use of antihypertensive medications (2. Do not take modafinil if pregnant and. Your data will only be used for strictly appropriated processing and for answering your request. Although most valves placed in the United States are still fixed-pressure valves, the programmable valve has become an. While it does not cure narcolepsy, it helps people stay awake during the day. Background and Purpose—. Modafinil (Provigil ®, Cephalon, Inc. Your doctor may recommend modafinil. These people tend to be female, 40-49 old, have been taking the drug for < 1 month, also take medication Xyrem, and have Multiple sclerosis. Introduction. Using adjustable. (1) Limitations of Use In OSA, PROVIGIL is indicated to treat excessive sleepiness and not as treatment for the underlying obstruction. There are 463 drugs known to interact with modafinil, along with 9 disease interactions, and 2 alcohol/food interactions. Dopamine is a “feel good” brain chemical that acts as the brain’s pleasure and reward system. ) is a product of Beximco Pharmaceuticals Ltd. What Can Modafinil Treat? This medication contains modafinil. If you need help remembering to take your dose of Provigil on time, try using a medication. Current Sleep Medicine Reports - Idiopathic hypersomnia is an incapacitating disorder with a profound impact on daytime performance and quality of life. In case of cancellation your data will be deleted immediately. A mechanical 'brake' is intended to prevent changes to the valve's performance level in a strong magnetic field. 41 reviews for modafinil to treat Obstructive Sleep Apnea/Hypopnea Syndrome: Rx: C 4: Generic name: modafinil systemic Brand name: Provigil Drug class: CNS stimulants. 92% of reviewers reported a positive experience, while 0% reported a. Anatomic Models Medicine & Life Sciences 12%. ) is a product of Beximco Pharmaceuticals Ltd. Differential pressure valves are a popular treatment modality, with evidence. ) Adderall comes in two forms, both of which. Modafinil . 0 Adjustment Tool 4 proGAV Adjustment Disc 4 proGAV Check-mate 0297 7 RECOMMENDATION OF PRESSURE LEVELS 7Depression: Modafinil is an anti-sleeping medication, and it keeps one awake for long periods; lack of sleep and disruption of the normal sleep-wake cycle can lead to the triggering of the onset of mental health issues. It is a psychotropic medication to improve alertness in people with sleep difficulties or work nights. 0 programmable valve in a paediatric population. Conclusions. I also have built up a tolerance to the 200mg so it has started to wear off about 4 hours after taking it and is a very hard medicine to get the dosage upped on. The ProGav Miethke shunt is composed of an adjustable ballon-spring valve unit and an integrated over-drainage compensating gravitational device (known as the shunt assistant). The proGAV is a position-dependent valve. He is the medical director at Alcohol Recovery Medicine. 126 reviews submitted with a 7. Provigil Warnings. ; Children under 6 years: Not recommended. Modafinil (Provigil) is a prescription medication used to improve wakefulness in people who have extreme sleepiness due to narcolepsy, obstructive. The proGAV®2. This study seeks to describe the utility of the proGAV®2. There are several Modafinil vendors that offer pharmaceutical-grade Modafinil products for very reasonable prices. The medication may also produce. 53 mmHg ml-1 min-1 (95% confidence limit: +/- 0. Hydrocephalus is the most prevalent neurosurgical problem encountered in the pediatric population [1,2,3]. You can go with a methylphenidate to dexmethylphenidate substitution (or vice versa). Methods All tests were performed using a whole-body 7T MRI system. The differential use was slightly larger when only studies in OSA were. INTRODUCTION. calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate. Nicotine psychopharmacology: addiction, cognition and neuroadaptation. Differential pressure valves are a popular treatment modality, with evidence suggesting that incorporation of gravitational units helps minimise over-drainage. Achieving decompression without CSF over-drainage remains a challenge in hydrocephalus. • Store PROVIGIL at room temperature between 68° and 77° F (20° and 25° C). If you are taking modafinil to treat narcolepsy or OSAHS, you will probably take it in the morning. In the United States, modafinil is FDA-approved for the treatment of the following in adults: narcolepsy, sleep work shift disorder, and obstructive sleep apnea (adjunct to continuous positive airway. Modafinil (Provigil): This medication is designed to encourage a feeling of wakefulness. A greater proportion of modafinil-treated patients required new or increased use of antihypertensive medication compared with those receiving placebo in a retrospective analysis (2. +৩২৫ মি. You can buy Provigil online from a variety of reputable retailers, but be sure to check with your doctor before starting any new medication. Counseling for adult ADHD generally includes psychological counseling (psychotherapy), education about the disorder and learning skills to help you. Modafinil may also be used for purposes not listed in this medication guide. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. BACKGROUND: Overdrainage is a common complication associated with shunt insertion in normal-pressure hydrocephalus (NPH) patients. S. See 17 for PATIENT COUNSELING INFORMATION and Medication Guide. Modafinil (Provigil; 200 mg once daily) This medication is not a stimulant but is used to improve wakefulness in patients with excessive sleepiness. Keep out of the reach of children. As a Schedule IV controlled substance, Provigil is illegal to use without prescription. diarrhea. Differential pressure valves are a popular treatment modality, with evidence suggesting that incorporation of gravitational units helps minimise over-drainage. Never share your medicine with anyone. Then the valve can be located on the patient‘s head with the forefinger. Medications Sometimes Used for Sleep Disruption. The proGAV 2. WE ARE THERE FOR YOU. Cytoprotective effects may occur through increases in bicarbonate ion (HCO. Adjusted for baseline scores. 2 out of 10 from a total of 509 ratings on Drugs. These effects are called interactions. Selling or giving away Provigil may harm others, and is against the law. EEG studies have shown modafinil increases high. Keep all medicine out of the reach of children. Since the last edition of this Black Book in 2016, a large number many new psychotropics have been approved by the FDA and are now in clinical use. ; Hepatic Impairment: No dose modification necessary. It is sometimes prescribed off-label for treating Attention deficit hyperactivity disorder in children, having no benefit in ADHD for adults. Ritalin. flushing or redness of the skin. Provigil is prescribed to increase wakefulness in patients with excessive sleepiness related to narcolepsy, shiftwork sleep disorder, and obstructive sleep apnea/hypopnea syndrome. It was first developed in the 1970s, but it wasn't approved for use in the United States until 1998. Avoid or Use Alternate Drug. It is a true game-changer and I thank God everyday for it. Modafinil, sold under the brand name Provigil, is a medication used primarily to treat sleep disorders like narcolepsy and sleep apnea. Introduction. 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